Ideal for that red carpet event or just a festive Saturday night, this is a favourite of make-up artists and celebrities. This causes the blood vessels to narrow and restricts the flow of blood through them. Qualitative and quantitative composition, 4.2 Posology and method of administration, 4.4 Special warnings and precautions for use, 4.5 Interaction with other medicinal products and other forms of interaction, 4.7 Effects on ability to drive and use machines, 6.6 Special precautions for disposal and other handling, 9. Remove contact lenses before use, allow at least 15 minutes before replacing them after use. The safety of chloramphenicol eye drops during pregnancy has not been established. Find out about Optrex eye drops to help care for your eyes Skip to: Primary Navigation , Dausch D et al. Anyone who uses contact lenses can also use this eye treatment. Chloramphenicol eye drops must not be administered to: Patients who have a history of hypersensitivity to chloramphenicol or to any other ingredient of the drops. Other Ingredients: Liquid Paraffin and White Petroleum. With scientifically proven ingredients such as Zinc, DHA* and Vitamin B2 to help maintain normal vision. Phenylmercuric nitrate may cause allergic reactions. Acquired resistance to chloramphenicol has been described in all the above species. Chloramphenicol is readily absorbed when given by mouth. This information is intended for use by health professionals, Excipients with known effect: Phenylmercuric nitrate, Boric Acid (and Borates) (0.135 mg boron/drop). Features. Bone marrow failure1, aplastic anaemia1,2, Vision blurred, eye pain, eye swelling, eye irritation. Optrex Itchy Eye Drops have been specially designed, using purified water and natural plant extracts to combat the irritation caused by pollen, housemites and other particles e.g. What is Optrex Double Action Dry & Tired Eye Drops? If no susceptibility test result is available, the choice of antibacterial agent should be influenced by local information on the likely prevalence of resistance to chloramphenicol in species that are commonly pathogenic in the eye. If excess product is applied to the eye the eye should be washed out with water and symptomatic treatment given. Optrex Eye Drops works by constricting the blood vessels in the eye. 10 ML | 47.50 per 100ML. For a full list of excipients, see section 6.1. Keep all medicines out of the sight and reach of children. Optrex red eyes eye drops provide temporary relief of redness and blood shot eyes. A busy work schedule, regular computer use, contact lenses, travelling, centrally heated environments and even make-up are just some of the things that can take a toll on your eyes, leaving them tired and uncomfortable. Do not use for more than 5 days without consulting your doctor. To bookmark a medicine you must sign up and log in. Instantly hydrate, lubricate and soothe dry eyes. Some newer allergy eye drops Klin Monatsbl Augenheilkd 2006: 223: 974-983. If this product is used following advice from a contact lens practitioner or doctor contact lenses should not be worn during the course of treatment. Benzalkonium chloride is highly soluble in water and it has as its active centre a nitrogen atom that carries a positive charge. **Versus all other current Optrex Eye Drops. Following topical application to the eye, chloramphenicol may be absorbed into the aqueous humour. Optrex Refreshing Eye Drops are specially designed to help soothe and revitalise tired, uncomfortable eyes. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard. Dusty, smoky atmospheres, eye strain and chlorine in swimming pools can make the eyes red and irritated. %PDF-1.4 % Optrex Sore Eye Drops, for the relief of minor eye Excipient with known effect: 0.1mg benzalkonium chloride. Naphazoline hydrochloride is a type of medicine called a sympathomimetic. If symptoms persist, see your healthcare professional. The course of treatment is 5 days. Our gentle yet effective products for Problem Eyes and Everyday Eye Care are specially formulated to meet your eye care needs, so whether your eyes are simply tired & in need of refreshment or you have a bacterial infection and need antibiotics Optrex has a solution. Blood concentrations of 10g per ml or more may be reached about 1 or 2 hours after a single dose of 1g by mouth, and blood concentrations of about 18.5g per ml have been reported after multiple 1g doses. No data on human fertility are available. Do not use if you are sensitive to any of the ingredients. The Double Action Eye Drops contain twice as many hydrating ingredients as the standard Optrex Eye Drops. Specially formulated long-lasting drops to instantly rehydrate dry, irritated or tired eyes. Ingredients Aqua, Hamamelis Virginia (Witch Hazel), Alcohol, Boric Acid, Glycerin, Sodium Borate, Benzalkonium Chloride To email a medicine you must sign up and log in. In order to buy non-prescription medicines you must be a registered user of our site as we are obliged to record your transaction history. Optrex intensive eye drops offer intensive dry eye symptom relief that lasts. The active ingredient, Sodium Cromoglicate, works by stopping the body from releasing histamine, the natural allergic response chemical that causes the reaction. Qualitative and quantitative composition. Optrex Eye Drops are medicated to relieve red, sore and inflamed eyes. If symptoms do not improve within 48 hours talk to your doctor, Seek further immediate medical advice at any time if symptoms worsen, Do not use if you are allergic to chloramphenicol or any of the ingredients, Discard any remaining eye drops after the five day course of treatment. Usage. Before using Optrex Eye Drops, inform your doctor about your current list of medications, over the counter products (e.g. Renal impairment has relatively little effect on the half-life of the active drug, due to its extensive metabolism, but may lead to accumulation of the inactive metabolites. Optrex Sore Eye Drops - Summary of Product Characteristics (SmPC) by Reckitt Benckiser Healthcare (UK) Ltd Hypersensitivity to any of the ingredients. When suggestions are available use up and down arrows to review and ENTER to select. It acts on alpha receptors in the walls of blood vessels. Eye drops, solution. Use only as directed. Each ml of eye drops contains. Chloramphenicol is widely distributed in body tissues and fluids; it enters the cerebrospinal fluid, giving concentrations of about 50% of those existing in the blood even in the absence of inflamed meninges; it diffuses across the placenta into the foetal circulation, into breast milk, and into the aqueous and vitreous humours of the eye. Chloramphenicol is absorbed systemically from the eye and systemic toxicity has been reported (see section 4.8). They should not be used by anyone who is allergic to any of the ingredients contained in the eye drops. Dausch D et al. Optrex Multi Action Eye Wash: Optrex Refreshing Eye Drops: Optrex Sore Eyes Drops (NZ):: D0176570 v3.2 Section 3. Do not use after expiry date. Usage and Instructions If you have any of these symptoms, then you are likely to have conjuntivitis: redness in the white part of your eye; red or swollen eyelids; sticky discharge that can make it difficult to open the eye in the morning; a feeling of grittiness or irritation of the affected eye(s). Patients with a family history of blood dyscrasias. Our gentle yet effective products for Problem Eyes and Everyday Eye Care are specially formulated to meet your eye care needs, so whether your eyes are simply tired & in need of refreshment or you have a bacterial infection and need antibiotics Optrex has a solution. Optrex Itchy Eye Drops: - Gently cleanse the eye's surface, washing away particles that can cause allergy and hay fever - Are specially designed to help relieve discomfort and irritation - Contain natural plant extracts - Safe for every day use Soothe and relieve itchy eyes Pollen, pet hair and dust mites can leave eyes feeling itchy, irritated and uncomfortable. Tips & Advice. GLYCERIN (aka glycerol, propane-1,2,3-triol, E422) Glycerine is a by product from the manufacture of soap and biodiesel. As with other ophthalmic solutions containing benzalkonium chloride, soft contact lenses should not be worn during the treatment period. Although the shelf life once opened is 28 days, patients should be advised to discard the medicine after a 5 day course of treatment. Blurring of vision can occur with the drops and patients should be warned not to drive or operate machinery unless their vision is clear. Optrex Dry Eye Drops have been designed to help your eyes tackle aspects of modern living such as driving, computer use, air conditioning, central heating and polluted environments. Product Features . ), allergies, pre-existing diseases, and current health conditions (e.g. Children under 2 years: this product is not recommended for children under 2 years of age. Optrex Allergy Eye Drops can be used to prevent, treat and soothe red, watery, puffy and itchy eyes caused by hayfever or allergies such as house mites and pet hairs. Leave at least 30 minutes between administrations of any other ophthalmic drugs. Keep out of the sight and reach of children. Do not use with another eye drop unless directed by your doctor or eye practitioner. Features of Optrex dry eye drops 10ml For dry eyes Longer lasting relief With Lutein & Zeaxanthin which make up the macular carotenoids. Sufficient chloramphenicol may be absorbed from the eye to appear in the systemic circulation. The following bacterial species are recognised conjunctival pathogens and may be susceptible to chloramphenicol. 1700 South Broadway, New Ulm, MN 56073. Chloramphenicol sodium succinate is, even in adults, only partially and variably hydrolysed, so that blood concentrations of chloramphenicol obtained after parenteral administration of the sodium succinate are often lower than those obtained after administration of chloramphenicol by mouth, with up to 30% of a dose excreted unchanged in the urine before hydrolysis can take place. Instantly hydrate, lubricate and soothe dry eyes. Excipients with known effect: Phenylmercuric nitrate, Boric Acid (and Borates) (0.135 mg boron/drop) For full list of excipients, see Section 6.1. Treatment of acute bacterial conjunctivitis. Optrex Eye Drops contains Naphazoline Hydrochloride as an active ingredient. 3. Keep out of reach of children. In severe bacterial conjunctivitis and in cases where infection is not confined to the conjunctivae, the topical use of chloramphenicol should be supplemented by appropriate systemic treatment. Home; About; Merchandise; Deals; Donate; Contact Us Avoid placing the top of the dropper in contact with the eyelid, eye or any other surface. A clear, slightly yellow solution. Dry eye syndrome can be caused by many aspects of modern living, from computer use to air conditioning. Patients should also be referred to their doctor if any of the following in his/her medical history apply: Previous conjunctivitis in the recent past, Eye surgery or laser treatment in the last 6 months, Current use of other eye drops or eye ointment. It allows continued monitoring of the benefit/risk balance of the medicinal product. Specific data on systemic absorption from this dosage presentation is not available. Tips & Advice. Optrex Infected eye drops contain an antibiotic called chloramphenicol. For adults and children over 3 years. Optrex Infected Eye Drops. OPTREX EYE LOTION Gentle soothing action. Localised symptoms such as eye irritation, pain or swelling, lacrimation or photophobia may occur. In view of the fact that chloramphenicol/metabolites are excreted in human milk and effects have been shown in breastfed newborns/ infants of treated women, the product should not be used during lactation. Safety Warning Important Do not use if you are allergic to any of the ingredients. RB Consumer Relations, PO Box 4644, SLOUGH, SL1 0NS, UK. When you have this Condition, the white part of one or both of your eyes will be red and/or your eyelids may be red or swollen. Start typing to retrieve search suggestions. Patients should seek advice before they discontinue use of the product. The half-life of chloramphenicol has been reported to range from 1.5 to 4 hours; the half-life is prolonged in patients with severe hepatic impairment and is also much longer in neonates. For serious eye problems or if symptoms persist or new symptoms arise, speak to your doctor, pharmacist or optician. pet hair. Specifications 10ml. Detailed information related to Optrex Eye Drops's uses, composition, dosage, side effects and reviews is listed below. Its cooling formulation soothes the irritation and calms the redness of bloodshot eyes, restoring normal blood flow. One drop instilled into the infected eye every 2 hours for the first 48 hours and 4 hourly thereafter. Optrex Hayfever Relief 2% w/v Eye Drops, for the relief and treatment of the eye symptoms of Hayfever, contains sodium cromoglicate Optrex Bloodshot Eye Drops, for temporary relief of redness of the eye due to minor eye irritations, contains witch hazel and naphazoline hydrochloride Usage Information Direction for Use: Adults and Children Rinse eye bath with Eye Wash immediately before and after use. To view the changes to a medicine you must sign up and log in. Optrex bloodshot eye drops relive redness caused by these minor eye irritations. This action reduces redness in the eyes. 6359469. White pigmented bottle of high density polyethylene/low density polyethylene mix with white pigmented low density polyethylene plug and red pigmented polyethylene tamper evident cap. This site uses cookies. However due to the prevalence of acquired resistance to chloramphenicol in these species, the results of susceptibility testing should be taken into account if these are available. 4.75. Optrex Eyedew Sparkling Eye Drops restore natural brightness to enhance your eyes' sparkle during the day Eyedew Sparkling Eye Drops restore natural brightness to reveal beautiful, clear eyes. Chloramphenicol is not generally active against the enterobacteriaceae and is not active against non-fermenters such as Pseudomonas aeruginosa. Within each frequency grouping, adverse events are presented in order of decreasing seriousness. *Dry, irritated, watery and tired symptoms due to disturbed lipid layer of the tear film, approximately 80% of dry eye cases. Optrex eye drops can help to prevent, soothe or treat eye problems but can also be included in your daily routine. Children aged 2 years and over: As above for adults. Qualitative and quantitative composition. Benzalkonium chloride is highly soluble in water and it has as its active centre a nitrogen atom that carries a positive charge. Aqua, Hamamelis Virginia (Witch Hazel), Alcohol, Boric Acid, Glycerin, Sodium Borate, Benzalkonium Chloride. To be used during waking hours only. Therefore, the patient should be referred to seek medical advice. Optrex Eye Wash with Eye Bath for tired, uncomfortable eyes is so versatile; it's a must-have for your first aid kit. The absorption, metabolism, and excretion of chloramphenicol are subject to considerable interindividual variation, especially in infants and children, making monitoring of plasma concentrations necessary to determine pharmacokinetics in a given patient. No dosage adjustments are required for elderly. If symptoms persist, see your healthcare professional. Name of the medicinal product. For external use only. Date of first authorisation/renewal of the authorisation. 4.4 Special warnings and precautions for use. Treatment should continue for 5 days even if symptoms improve. Optrex red eyes eye drop Optrex Eye Wash: - Washes away particles to cleanse the eye. 2017 Reckitt Benckiser - All Rights Reserved, Always read the label. Optrex Infected Eye Drops contains the active ingredient Chloramphenicol and is used in both adults and children to treat acute bacterial conjunctivitis, which is an infection of the outer surface of the eye that causes redness, discomfort and discharge from the eye. Alternatively, the Optrex Actimist spray is clinically proven to last up for up to 4 hours. Patients with pre-existing bone-marrow depression or patients who have experienced myelosuppression during previous exposure to chloramphenicol. Frequencies are defined as: Very common (1/10); Common (1/100 and <1/10); Uncommon (1/1000 and <1/100); Rare (1/10,000 and <1/1000); Very rare (< 1/10,000); Not known (cannot be estimated from the available data). Choramphenicol palmitate is hydrolysed to chloramphenicol in the gastrointestinal tract prior to absorption, and the sodium succinate, which is given parenterally is probably hydrolysed to free drug mainly in the liver, lungs, and kidneys; such hydrolysis may be incomplete in infants and neonates, contributing to the variable pharmacokinetics in this age group. These Optrex Eye Drops are suitable to be used by people who are suffering from dry eyes. By continuing to browse the site you are agreeing to our policy on the use of cookies. Always read the label. When the eyes are red it is usually because more blood than normal is flowing through the small blood vessels of the eye. Optrex Intensive Eye Drops - 10ml; Optrex Intensive Eye Drops - 10ml. Distilled witch hazel has cooling and mild astringent actions that soothe irritated eyes. Chloramphenicol is excreted mainly in the urine but only 5 to 10% of an oral dose appears unchanged; the remainder is inactivated in the liver, mostly by conjugation with glucorinic acid. vitamins, herbal supplements, etc. Optrex Double Action Dry & Tired Eye Drops is an eye treatment that is designed to restore moisture in the eyes. Optrex red eyes eye drops contain two active ingredients, naphazoline hydrochloride and hamamelis water, otherwise known as distilled witch hazel. 3 This can include rashes, fever, angioedema, urticaria and anaphylaxis. Do not swallow the solution. Storage. Chloramphenicol 0.5% w/v. Description of Selected Adverse Reactions: 1 Bone marrow failure, including the idiosyncratic type of irreversible and fatal aplastic anaemia that is recognised to occur with systemic therapy, has been reported in association with topical administration of chloramphenicol. Optrex ActiMist 2in1 Eye Spray For dry & irritated eyes (dry & irritated eyes due to disturbed lipid layer of the tear film, approx 80% of dry eye cases). Do not use if you are allergic to any of the ingredients. OPTREX As a leading eye care expert,** Optrex has created a comprehensive range of effective products to help you maintain your eye health. Patients should be referred to a doctor if any of the following apply: Eye inflammation associated with a rash on the scalp or face. 2. Most commonly this is mediated by bacterial production of a chloramphenicol acetyl transferase that inactivates the drug. If irritation persists seek medical advice. Up to about 60% in the circulation is bound to plasma protein. 2 This can include neutropenia and thrombocytopenia. Pharmacotherapeutic group: Sensory organs; Ophthalmologicals; Antiinfectives; Antibiotics; Chloramphenicol; Chloramphenicol is a broad spectrum bacteriostatic antibiotic active against a wide variety of gram-negative and gram-positive organisms. Continue, 2. Optrex Rehydrating Eye Drops for Dry Eyes 10ml Product ID: 2653553. Use only as directed. Do not give to a child less than 2 years old as this medicine contains boron and may impair fertility in the future. Our eye drops can help treat a range of eye conditions, including dry eyes, conjunctivitis and hayfever eyes. 3. Toxic epidermal necrolysis have been reported very rarely in association with the use of chloramphenicol (see section 4.8). $7.50 Do not use if you are allergic to any of the ingredients. Keep out of the sight and reach of children. The macula of the eye is responsible for our central vision which is used to see shapes, colour and details. Store below 25oC. Optrex intensive eye drops offer intensive dry eye symptom relief that lasts. Optrex Bacterial Conjunctivitis 1% w/w Eye ointment 2. If symptoms persist or worsen after 48 hours, or have not resolved within 5 days, consult a healthcare professional. They should not be used by anyone who is allergic to any of the ingredients contained in the eye drops. Dry eye symptom relief that lasts. Usage Information Direction for Use: Adults and Children Rinse eye bath with Eye Wash immediately before and after use. Not suitable for use with hydrophilic (soft) contact lenses. Continue typing to refine. Soft contact lenses should not be replaced for 24 hours after completing the treatment. Do not use if you are allergic to any of the ingredients. Chloramphenicol exerts its antibacterial effect by binding to bacterial ribosomes and inhibiting bacterial protein synthesis at an early stage. ).Some health conditions may make you more susceptible to the side-effects of the drug. Optrex itchy eye drops are specially formulated eye drops, which relieve the irritation caused by pollen and refresh sensitive, uncomfortable eyes. About 3% is excreted in the bile. For dry, irritated & tired eyes Lasting protection from discomfort. The key ingredient in allergy eye drops is a drug called an antihistamine, which blocks histamines from doing their work and prevents allergy symptoms. Warnings or Restrictions. Klin Monatsbl Augenheilkd 2006: 223: 974-983. Suitable for Use with contact lenses. Mon - Sat from 11 am - 2 pm; Closed Sun. Sodium cromoglicate eye drops contains benzalkonium chloride. The active ingredients in these eye drops will make the whites of your eyes whiter than you've ever seen them before. As this product is for sale without prescription it is not recommended for use during pregnancy. There are no preclinical data of relevance to the prescriber which are additional to that already included. Because they contain natural plant extracts and are balanced at the natural pH of tears the drops are suitable enough for every day use. The use of topical chloramphenicol may occasionally result in overgrowth of non-susceptible organisms including fungi. Balanced at the natural pH level of tears and enriched with plant extracts, it gently helps to remove dust, make-up and other particles that can easily get trapped on the surface of your eye. Reporting suspected adverse reactions after authorisation of the medicinal product is important. If you are using any other form of medication, then speak to a doctor or Chemist 4 U pharmacist before using. x. Pharmacy product . *Dry, irritated, watery and tired symptoms due to disturbed lipid layer of the tear film, approximately 80% of dry eye cases. pregnancy, upcoming surgery, etc. Treatment must be discontinued immediately in such cases. Composition and ingredient information boric acid 3 10043-35-3 glycerol 3 56-81-5 Ingredient name CAS number Other Non-hazardous ingredients to 100% Substance/mixture : Features of Optrex red eyes eye drops 10ml. 1. If any new infection appears during treatment, the patient should be referred to the doctor. Optrex ActiMist 2in1 Eye Spray For dry & irritated eyes (dry & irritated eyes due to disturbed lipid layer of the tear film, approx 80% of dry eye cases). Sodium cromoglicate can be used prophylactically. However, most is reabsorbed and only about 1%, mainly in the inactive form, is excreted in the faeces. Topical application to eyes has been associated with mercurialentis and atypical band keratopathy. It is used to treat bacterial infections that affect the front surfaces of the eye. Features of Optrex dry eye drops 10ml For dry eyes Longer lasting relief Lubricates and soothe dry eyes . Relieve redness of the eyes They should not be used by anyone who is allergic to any of the ingredients contained in the eye drops. Optrex ProVision Eye Health Food Supplement. The most common type of infection in this area is called acute bacterial conjunctivitis. boric acid 3 10043-35-3 glycerol 3 56-81-5 Ingredient name CAS number Other Non-hazardous ingredients to 100% Substance/mixture : Occupational exposure limits, if available, are listed in Section 8. Refresh. Keep all medicines out of the sight and reach of children. Qualitative and quantitative composition Each gram of ointment contains 10 mg Chloramphenicol (1% w/w) For full list of excipients, see Section 6.1. Prolonged or frequent intermittent topical application of chloramphenicol should be avoided since it may increase the likelihood of sensitisation and emergence of resistant organisms. In view of the relatively small amount of chloramphenicol in chloramphenicol eye drops, overdosage with this product is unlikely to constitute a hazard. Do not use during pregnancy or breast-feeding. Discard 28 days after opening. Optrex Eye Wash: - Washes away particles to cleanse the eye. Active substance: 20 mg sodium cromoglicate (2.0% w/v), (one drop contains 0.7mg sodium cromoglicate). Adverse events which have been associated with topical chloramphenicol are given below, tabulated by system organ class and frequency. Tired, uncomfortable eyes conditions ( optrex eye drops ingredients it allows continued monitoring of the eye appear. Not use if you are sensitive to any of the eye pregnancy has not been established small. Swelling, eye swelling, lacrimation or photophobia may occur children under 2 years and over: as for Of infection in this area is called acute bacterial conjunctivitis replaced for 24 after 4 hours suspected adverse reactions after authorisation of the ingredients contained in the walls of blood vessels narrow! May occur can occur with the drops and patients should be warned not drive. By product from the eye the eye and systemic toxicity has been reported very rarely in association the! Or new symptoms arise, speak to your doctor, pharmacist or optician with and The inactive form, is excreted in the eyes red and irritated offer! Benefit/Risk balance of the eye drops works by constricting the blood vessels eye be! 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